MORTON C. CREDITOR, M.D.; HARRY W. MCCURDY, M.D.
Infectious mononucleosis is a disease of undetermined etiology which generally pursues a benign course. Consideration of specific therapy is rarely required. However, fatalities due to infectious mononucleosis have been reported. Fatal cases include those with complications such as Guillain-Barrésyndrome,1 diffuse neurologic involvement,2 respiratory obstruction,3 splenic rupture4 and generalized "toxemia."5
Treatment of infectious mononucleosis is symptomatic. However, reports of cortisone- and corticotropin-treated mononucleosis can be found in the literature. In many, treatment was started because of serious complications in which death seemed imminent; these included neurologic involvement,6 respiratory obstruction7 and generalized "toxemia."8 In each situation a prompt and dramatic response to
CREDITOR MC, MCCURDY HW. SEVERE INFECTIOUS MONONUCLEOSIS TREATED WITH PREDNISOLONE1. Ann Intern Med. ;50:218–222. doi: 10.7326/0003-4819-50-1-218
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Published: Ann Intern Med. 1959;50(1):218-222.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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