F. R. MCCRUMB JR., M.D.
Measles was first transmitted artificially from man to man in 1758 by Home,1 who exposed skin incisions of nonimmune volunteers to blood from patients ill with the disease. In 1905 Hektoen2 injected fresh blood from patients with measles subcutaneously into two individuals who developed measles 11 and 13 days later, respectively. Susceptibility of species of the genus Macaca was established by the experiments of Goldberger and Anderson in 1911,3 when they demonstrated that more than 50% of monkeys inoculated with blood and nasopharyngeal washings from patients with measles developed fever, catarrhal symptoms and exanthem. Transmission of this disease through six
MCCRUMB FR. RECENT ADVANCES IN THE STUDY OF MEASLES VIRUS. Ann Intern Med. ;50:522–526. doi: 10.7326/0003-4819-50-2-522
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Published: Ann Intern Med. 1959;50(2):522-526.
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