SOL SHERRY, M.D.; ANTHONY P. FLETCHER, M.D.; NORMA ALKJAERSIG, M.S.
Intravascular thrombi in animals may be dissolved by activating the naturally occurring fibrinolytic enzyme system.1, 2 In figure 1 (on the left), there is illustrated an experimental thrombus in the femoral artery of a dog five days after its production. The artery is cut in a semilongitudinal fashion, and evidence of early organization of the well formed thrombus is apparent. The section of artery shown on the right in figure 1 was taken from a second streptokinase-treated animal in which an experimental thrombus had been produced. Both specimens were taken after the same interval. The lumen is patent in this
SHERRY S, FLETCHER AP, ALKJAERSIG N. DEVELOPMENTS IN FIBRINOLYTIC THERAPY FOR THROMBO-EMBOLIC DISEASE12. Ann Intern Med. ;50:560–570. doi: 10.7326/0003-4819-50-3-560
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Published: Ann Intern Med. 1959;50(3):560-570.
Cardiology, Hospital Medicine.
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