GEORGE E. FARRAR JR., M.D., F.A.C.P.
Nolle Nocere, primum nolle nocere: the first principle of therapeutics. "Do no harm"—literally, "To be unwilling to do harm." This is the principle on which rests public confidence in the physician.
This first principle has stood firm throughout the centuries; only the connotation has changed. But this change, largely the result of the many outstanding advances in pharmacology which we have seen in our time, has been so great as to nearly obscure the principle. The lines of Pope, "Be not the first by whom the new are tried, nor yet the last to lay the old aside," are still
FARRAR GE. NOLLE NOCERE THE RESPONSIBILITY OF THE PHARMACEUTICAL INDUSTRY(NOLLE NOCERE THE RESPONSIBILITY OF THE PHARMACEUTICAL INDUSTRY*). Ann Intern Med. 1959;50:829–834. doi: 10.7326/0003-4819-50-3-829
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Published: Ann Intern Med. 1959;50(3):829-834.
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