BERT L. VALLEE, M.D.; WARREN E. C. WACKER, M.D.; ANTHONY F. BARTHOLOMAY, SC.D.; FREDERIC L. HOCH, M.D.
Zinc is present in all living organisms and is essential as a nutrient for plants and animals.13, 27 The normal human dietary intake of zinc is about 10 to 15 mg. a day. The stool is the major excretory route; it contains about 10 mg. a day, whereas the urine contains only about 0.4 to 0.5 mg. a day.17 The amount of zinc in different human organs varies between 10 and 200 μg. per gram of wet tissue.30 The human liver contains 50 to 60 μg. of zinc per gram.34 The identification of zinc as a component of carbonic anhydrase
VALLEE BL, WACKER WEC, BARTHOLOMAY AF, HOCH FL. ZINC METABOLISM IN HEPATIC DYSFUNCTION(ZINC METABOLISM IN HEPATIC DYSFUNCTION*†)(ZINC METABOLISM IN HEPATIC DYSFUNCTION*†). Ann Intern Med. 1959;50:1077–1091. doi: 10.7326/0003-4819-50-5-1077
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Published: Ann Intern Med. 1959;50(5):1077-1091.
Gastroenterology/Hepatology, Liver Disease.
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