SHELDON E. GREISMAN, M.D.
The therapeutic usefulness of vasopressor agents, although employed many years for correction of various shock syndromes, remains highly controversial. Some investigators disapprove of their indiscriminate use;1-3 others have advocated such therapy routinely.4, 5 The basis for the divergence of opinion may be traced to variation in interpretation of the clinical evidence. Conclusions favoring the routine employment of vasopressor therapy often fail to consider that: (1) improvement of the systemic arterial blood pressure is not synonymous with therapeutic benefit; in some instances "cures" have been ascribed to vasopressor drugs although the ultimate outcome was fatal; (2) lessening of cyanosis, though
GREISMAN SE. THE PHYSIOLOGIC BASIS FOR VASOPRESSOR THERAPY DURING SHOCK1. Ann Intern Med. ;50:1092–1114. doi: 10.7326/0003-4819-50-5-1092
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Published: Ann Intern Med. 1959;50(5):1092-1114.
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