JOHN J. KELLY, M.D.; HENRY H. SHERK, M.D.
Three cases of myxedema with terminal coma were described in 1888 by a committee of the Clinical Society of London.1 Although similar cases of "myxedema coma" have been reported subsequently,2, 3 little attention was directed specifically toward this complication until 1953, when Le Marquand et al. presented two such patients.4 Since then, 23 cases have been described.
In view of the rare occurrence of myxedema coma, it was deemed appropriate to report another patient who became profoundly myxedematous over a period of years, lapsed into coma suddenly, and died shortly after admission to the hospital. Necropsy findings are described and
KELLY JJ, SHERK HH. MYXEDEMA COMA(MYXEDEMA COMA*). Ann Intern Med. 1959;50:1303–1309. doi: 10.7326/0003-4819-50-5-1303
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Published: Ann Intern Med. 1959;50(5):1303-1309.
Endocrine and Metabolism, Thyroid Disorders.
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