LAMAR E. CREVASSE, M.D.; R. BRUCE LOGUE, M.D., F.A.C.P.
Despite the fact that myxedema is a time-worn subject, it is so insidious and protean in its manifestations that even today the average duration of symptoms prior to recognition is 4.8 years.1 A frequent but poorly appreciated manifestation is that of myxedematous peripheral neuropathy. This complication has been commented upon infrequently and vaguely in the past.2, 3, 4 In our recent clinical experience with more than 250 patients treated with radioactive iodine to induce myxedema for its beneficial effects on cardiovascular diseases,5 we have been impressed by the high incidence of distressing symptoms related to peripheral neuropathy. To determine its
CREVASSE LE, LOGUE RB. PERIPHERAL NEUROPATHY IN MYXEDEMA1. Ann Intern Med. ;50:1433–1437. doi: 10.7326/0003-4819-50-6-1433
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Published: Ann Intern Med. 1959;50(6):1433-1437.
Endocrine and Metabolism, Neurology, Neuropathy, Thyroid Disorders.
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