JAMES M. STORMONT, M.D.; JOSEPH E. MACKIE, M.D.; EDWARD H. KASS, M.D., F.A.C.P.; CHARLES S. DAVIDSON, M.D.. F.A.C.P.
The role of bacteria in the pathogenesis of liver disease is uncertain. In ascending cholangitis, bacteria frequently invade the liver; however, in other types of liver disease, bacterial invasion of the liver often has been postulated but has not been demonstrated. The action of intestinal bacteria in the production of experimental cirrhosis in rats has been studied,1, 2 but it is difficult to transfer these findings to human cirrhosis.
Postmortem liver and portal vein cultures in the human have grown out intestinal bacteria within 30 minutes after death.3-5 Cultures of the liver by means of the Vim-Silverman biopsy needle, peritoneoscopic
STORMONT JM, MACKIE JE, KASS EH, DAVIDSON CS. BACTERIOLOGIC CULTURE OF THE DISEASED HUMAN LIVER12. Ann Intern Med. ;51:17–22. doi: 10.7326/0003-4819-51-1-17
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Published: Ann Intern Med. 1959;51(1):17-22.
Gastroenterology/Hepatology, Liver Disease.
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