IRVINE H. PAGE, M.D., F.A.C.P.; HARRIET P. DUSTAN, M.D.; EUGENE F. POUTASSE, M.D.
With Richard Bright's clinical observations, kidney disease and hypertension became indissolubly, though obscurely, associated; this association seemed to become more tangible when Goldblatt produced hypertension in the dog by putting a clamp on the renal artery. Although the relationship of the kidneys to hypertension was then more clearly defined, the mechanisms of this relationship have not yet been disclosed. Opinion in the last 25 years has ranged all the way from the one extreme, of believing that essential and malignant hypertension are due entirely to renal disease, to the other extreme, of denying all relationship. Like many extreme stands, these
PAGE IH, DUSTAN HP, POUTASSE EF. MECHANISMS, DIAGNOSIS AND TREATMENT OF HYPERTENSION OF RENAL VASCULAR ORIGIN1. Ann Intern Med. 1959;51:196–211. doi: 10.7326/0003-4819-51-2-196
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Published: Ann Intern Med. 1959;51(2):196-211.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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