JOHN F. MURRAY, M.D.; JOHN J. KELLY JR., M.D.
At the beginning of the present century a keen interest developed in the physiologic properties of the recently discovered hormones of the adrenal medulla and thyroid. In 1908 Eppinger, Falta and Rudinger1 suggested that the thyroid hormone potentiated the physiologic effects of epinephrine. In 1918 Goetsch,2 reviewing diagnostic methods for hyperthyroidism, drew attention to this early report, and to more recent ones by Cannon and Cattell3 and Levy,4 which were concerned with the interrelationships of the adrenal medulla, the sympathetic nervous system and the thyroid. So impressed was Goetsch by the increased sensitivity of the thyrotoxic subject to epinephrine that
MURRAY JF, KELLY JJ. THE RELATION OF THYROIDAL HORMONE LEVEL TO EPINEPHRINE RESPONSE: A DIAGNOSTIC TEST FOR HYPERTHYROIDISM1. Ann Intern Med. 1959;51:309–321. doi: 10.7326/0003-4819-51-2-309
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Published: Ann Intern Med. 1959;51(2):309-321.
Endocrine and Metabolism, Thyroid Disorders.
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