JOHN F. O'CONNOR, M.D.
Systemic lupus erythematosus is an inflammatory process the etiology of which is unknown. It involves primarily the smaller blood vessels and the connective tissue; therefore, lesions can be found in any organ. It is seen most frequently in young adult females. The clinical picture necessarily varies with the acuteness of the process and the organ involvement. Fever with leukopenia, polyarthritis, nephritis, polyserositis and verrucous endocarditis are commonly found. The prognosis in all cases is grave. The disease may terminate in a few weeks, or may run a remittent course over a period of many years. Steroids have been particularly effective
O'CONNOR JF. PSYCHOSES ASSOCIATED WITH SYSTEMIC LUPUS ERYTHEMATOSUS1. Ann Intern Med. ;51:526–536. doi: 10.7326/0003-4819-51-3-526
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Published: Ann Intern Med. 1959;51(3):526-536.
Lupus Erythematosus, Rheumatology.
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