ARNOLD G. BLUMBERG, M.D., F.A.C.P.; HENRY L. ROSETT, M.D.; ALAN DOBROW, M.D.
The physician prescribing sedative drugs to an emotionally disturbed individual must always be conscious of the danger of overdosage by accident or by suicidal intent. Although meprobamate has been clinically demonstrated to be one of the safest drugs in terms of the relative absence of toxic actions of large doses, the literature contains an increasing number of reports of serious sequelae to meprobamate overdosage. Two cases where the overdosage with meprobamate was attended with severe collapse and hypotension are presented here. The clinical course and the method of treatment in both cases are of interest, and suggest the mode
BLUMBERG AG, ROSETT HL, DOBROW A. SEVERE HYPOTENSIVE REACTIONS FOLLOWING MEPROBAMATE OVERDOSAGE1. Ann Intern Med. ;51:607–612. doi: 10.7326/0003-4819-51-3-607
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Published: Ann Intern Med. 1959;51(3):607-612.
Hospital Medicine, Neurology.
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