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Many of the drugs which the physician routinely uses today may cause distressing and dangerous toxic manifestations even when used in the smallest doses. One need only mention new and potent steroids, antibiotics, phenothiazine derivatives, antimalarials, anticonvulsants, etc. We are in an era of new synthetic agents of great potency, and potency always carries the risk of serious side-effects. Use of potent medicaments requires that new drugs be studied more carefully than ever before, and vast amounts of data from animal experimentation must be reviewed by toxicologists, pathologists, pharmacologists, biochemists, clinicians, and many other specialists before the drug can be
A Symposium on the Evaluation of Drug Toxicity.. Ann Intern Med. ;51:834–835. doi: 10.7326/0003-4819-51-4-834_2
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Published: Ann Intern Med. 1959;51(4):834-835.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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