JESSIE MARMORSTON, M.D.; FREDERICK J. MOORE, M.D.; OSCAR MAGIDSON, M.D.; OLIVER KUZMA, M.D.; JACK J. LEWIS, M.D.
It has been well established1-8 that administration of estrogen to men or women with myocardial infarction tends to raise the serum phospholipids and to lower the serum cholesterol and the cholesterol/phospholipid (C/P) ratio. In a recent communication9 we noted that prolonged administration of ethinyl estradiol to postmenopausal women with myocardial infarction resulted in changes in these serum lipids, chiefly in those in whom the levels were initially abnormal. Thus estrogen therapy in effect tended to bring these serum lipids to "normal" levels.
We wish to report here the effects upon cholesterol and phospholipids of long-term estrogen therapy, using clinically well
MARMORSTON J, MOORE FJ, MAGIDSON O, KUZMA O, LEWIS JJ. EFFECTS OF LONG-TERM ESTROGEN THERAPY ON SERUM CHOLESTEROL AND PHOSPHOLIPIDS IN MEN WITH MYOCARDIAL INFARCTION(EFFECTS OF LONG-TERM ESTROGEN THERAPY ON SERUM CHOLESTEROL AND PHOSPHOLIPIDS IN MEN WITH MYOCARDIAL INFARCTION*†)(EFFECTS OF LONG-TERM ESTROGEN THERAPY ON SERUM CHOLESTEROL AND PHOSPHOLIPIDS IN MEN WITH MYOCARDIAL INFARCTION*†). Ann Intern Med. 1959;51:972–982. doi: 10.7326/0003-4819-51-5-972
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Published: Ann Intern Med. 1959;51(5):972-982.
Acute Coronary Syndromes, Cardiology, Coronary Heart Disease, Coronary Risk Factors, Dyslipidemia.
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