H. E. DEPREE, M.D., F.A.C.P.; M. J. HICKMAN, M.D.
Familial congenital methemoglobinemia is an unusual disease state. A total of somewhat over 100 cases has been reported2 in the literature, and only 13 families where multiple members have the disease (familial form).
It is our impression that clinicians in the private practice of medicine often share a feeling that the unusual diseases appear, mostly if not entirely, in the large institutions or centers of medicine. This feeling is gained principally from the reporting of diseases and their incidence in the literature, which must of necessity come out of adequately large series of cases, specialized diagnostic facilities, and other situations
DEPREE HE, HICKMAN MJ. FAMILIAL CONGENITAL METHEMOGLOBINEMIA: REPORT OF A CASE AND FAMILY STUDY1. Ann Intern Med. 1959;51:1078–1084. doi: 10.7326/0003-4819-51-5-1078
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Published: Ann Intern Med. 1959;51(5):1078-1084.
Cardiology, Hospital Medicine.
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