RICHARD W. DYKE, M.D., F.A.C.P.; CLAYTON E. WOOD, M.D.; SOPHOCLES D. MARTY, M.D.
Reports of successful means of treatment for localized pretibial myxedema are of interest because of its close relationship with progressive exophthalmos, and the possibility that the same agent might likewise reduce progressive exophthalmos. Evaluation of therapy for both conditions must be done with care because of the spontaneous improvement which may occur with both, and because chronic existence of both may be associated with permanent changes from fibrosis.9, 34, 36
First described in the English literature by Watson-Williams in 1895, localized pretibial myxedema has since been discussed frequently by dermatologists and, more recently, by others.1-18 Research concerning the pathology and
DYKE RW, WOOD CE, MARTY SD. LOCALIZED PRETIBIAL MYXEDEMA: REPORT OF TWO CASES TREATED WITH HYDROCORTISONE BY LOCAL INJECTION1. Ann Intern Med. 1959;51:1097–1103. doi: 10.7326/0003-4819-51-5-1097
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Published: Ann Intern Med. 1959;51(5):1097-1103.
Endocrine and Metabolism, Thyroid Disorders.
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