LEO J. CASS, M.D.
The high incidence of obesity in our population presents a definite public health problem. It is estimated that approximately 20 million people in the United States are clinically obese, and that 5 million of these weigh at least 20% above the optimum. The magnitude of the problem is presented in the insurance statistics, which clearly define the increased mortality rates for overweight individuals, especially those beyond the age of 45. Obesity is associated with increased susceptibility to cardiovascular disease, diabetes and gall-bladder disease, and of course represents an additional risk in surgery.1
Although there are recognized hereditary, constitutional and hormonal
CASS LJ. EVALUATION OF APPETITE SUPPRESSANTS1. Ann Intern Med. ;51:1295–1302. doi: 10.7326/0003-4819-51-6-1295
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Published: Ann Intern Med. 1959;51(6):1295-1302.
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