ANTHONY J. RICHTSMEIER, M.D., F.A.C.P.
Hypercalcemia occurs in sarcoidosis with sufficient frequency to merit special consideration.1 Likewise, the gastrointestinal symptom complex of hypercalcemia has received attention in recent years.2, 3 Gastrointestinal symptoms as a primary presenting symptom of hypercalcemia of sarcoidosis have been mentioned only infrequently in many of the articles reviewed. Failure to recognize this important diagnostic clue may lead to erroneous interpretation, causing exaggeration of symptoms, as noted in the patient here reported.
Hypercalcemia, when discovered, usually leads the clinician first to consider primary hyperparathyroidism, hypervitaminosis D, metastatic malignancy and multiple myeloma.4 Less common causes include the "milk alkali syndrome of Burnett," Paget's
RICHTSMEIER AJ. THE SYMPTOMS OF HYPERCALCEMIA ASSOCIATED WITH SARCOIDOSIS MASQUERADING AS PEPTIC ULCER1. Ann Intern Med. ;51:1371–1378. doi: 10.7326/0003-4819-51-6-1371
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Published: Ann Intern Med. 1959;51(6):1371-1378.
Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
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