JOSEPH R. NORA, M.D.; JOHN M. LEVITSKY, M.D.; HYMAN J. ZIMMERMAN, M.D., F.A.C.P.
Pituitary insufficiency is a rare complication of sarcoidosis.1, 2 Diabetes insipidus due to infiltration of the posterior lobe of the pituitary or hypothalamus has been reported by Tillgren,3 Longcope4 and others. Anterior pituitary insufficiency has been reported even less frequently.5, 6 The coexistence of diabetes insipidus and anterior pituitary dysfunction, as reported below, is a unique complication of sarcoidosis. The patient described illustrates some of the endocrine interrelationships involved in diuresis and antidiuresis.
This 38 year old Negro male steward had been in good health until one year prior to his admission to the hospital, at which time
NORA JR, LEVITSKY JM, ZIMMERMAN HJ. SARCOIDOSIS WITH PANHYPOPITUITARISM AND DIABETES INSIPIDUS1. Ann Intern Med. ;51:1400–1409. doi: 10.7326/0003-4819-51-6-1400
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Published: Ann Intern Med. 1959;51(6):1400-1409.
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