YALE RABINOWITZ, M.D.; WILLIAM DAMESHEK, F.A.C.P.
We have previously emphasized the close relationship between idiopathic thrombocytopenic purpura (I.T.P.) and systemic lupus erythematosus (S.L.E.), and have suggested that I.T.P. is often a prodrome of the larger syndrome. Actually, purpura has been known in systemic lupus erythematosus (hereafter designated S.L.E.) since early descriptions of the disease.28, 39, 40, 41 Kaposi28 was perhaps the first to remark on the association of lupus and purpura. Tumulty51 and Harvey,23 in their reviews of the history of S.L.E., have stressed Osler's understanding of the systemic nature of the disease, which he called "erythema exudativum multiforme," and his awareness of the occurrence of
RABINOWITZ Y, DAMESHEK W. SYSTEMIC LUPUS ERYTHEMATOSUS AFTER "IDIOPATHIC" THROMBOCYTOPENIC PURPURA: A REVIEW.: A study of systemic lupus erythematosus occurring after 78 splenectomies for "idiopathic" thrombocytopenic purpura, with a review of the pertinent literature12. Ann Intern Med. ;52:1–28. doi: 10.7326/0003-4819-52-1-1
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Published: Ann Intern Med. 1960;52(1):1-28.
Lupus Erythematosus, Rheumatology.
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