RICHARD W. HILL, M.D.; EDWIN D. BAYRD, M.D.
Subacute bacterial endocarditis often presents a diagnostic problem. The patient with a history of valvular heart disease who experiences the insidious onset of intermittent fever, chills and sweats, signs of peripheral embolism, splenomegaly, and changing heart murmurs presents no such difficulty, and the diagnosis becomes obvious when the results of blood cultures are positive. It is the patient who has atypical findings and whose blood cultures repeatedly yield negative results who presents a difficult problem in evaluation and management.
Subacute bacterial endocarditis with sterile blood cultures has been reviewed elsewhere.1-4 However, the presence or absence of reticuloendothelial cells of the
HILL RW, BAYRD ED. PHAGOCYTIC RETICULOENDOTHELIAL CELLS IN SUBACUTE BACTERIAL ENDOCARDITIS WITH NEGATIVE CULTURES1. Ann Intern Med. ;52:310–319. doi: 10.7326/0003-4819-52-2-310
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Published: Ann Intern Med. 1960;52(2):310-319.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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