JOEL H. RICHERT; JAMES A. WIER; JOHN M. SALYER; JAMES C. BEYER
Over the years the policy has evolved of simply accepting tuberculosis as the etiology of pleural effusion unless there is another well documented cause or unless the individual remains persistently tuberculin-negative. Making such unsubstantiated diagnoses has troubled physicians, especially in the military services, and has stimulated many studies aimed at increasing the accuracy of diagnosis. In recent years, attention has shifted from characteristics of pleural fluid to pleural biopsies. The microscopic examination of pleural tissue provides a convenient division into granulomatous and nongranulomatous cases. Bacteriologic studies of pleural tissue have confirmed the diagnosis of tuberculosis in many of the granulomatous
RICHERT JH, WIER JA, SALYER JM, BEYER JC. THE RELIABILITY OF TISSUE DIAGNOSIS OF PLEURISY: A PRELIMINARY REPORT1. Ann Intern Med. ;52:320–325. doi: 10.7326/0003-4819-52-2-320
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Published: Ann Intern Med. 1960;52(2):320-325.
Infectious Disease, Pulmonary/Critical Care.
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