J. GORDON BARROW, M.D., F.A.C.P.; CARROLL B. QUINLAN, M.D.; GERALD R. COOPER, M.D.; VIRGINIA S. WHITNER, M.S.; MARY H. R. GOODLOE, B.S.
Prior to World War II, atherosclerosis was regarded primarily as an aging process, rather than as a disease entity. Although chemical analyses of atheromata by Windaus in 19101 revealed their high lipid and cholesterol content, and Anitschkow in 19132 demonstrated that atheromatosis could be induced in laboratory animals by feeding them a high cholesterol diet, comparatively little research was directed toward determining the etiology of atherosclerosis.
During the last decade, however, investigators have become increasingly convinced that atherosclerosis is an actual disease process.3, 4, 7 It is now being studied from many points of view, but the approach which will
BARROW JG, QUINLAN CB, COOPER GR, WHITNER VS, GOODLOE MHR. STUDIES IN ATHEROSCLEROSIS. III. AN EPIDEMIOLOGIC STUDY OF ATHEROSCLEROSIS IN TRAPPIST AND BENEDICTINE MONKS: A PRELIMINARY REPORT12. Ann Intern Med. ;52:368–377. doi: 10.7326/0003-4819-52-2-368
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Published: Ann Intern Med. 1960;52(2):368-377.
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