HERBERT O. SIEKER, M.D.; ALBERT HEYMAN, M.D., F.A.C.P.; RICHARD I. BIRCHFIELD, M.D.
The close association between hypersomnolence and alterations in ventilatory function has recently received much attention. Abnormal states of somnolence associated with "central" hypoventilation have been described in a variety of conditions, such as marked obesity,1, 2 barbiturate intoxication,3 myotonic dystrophy4 and encephalitis.5, 6 In a few patients the hypoventilation phenomenon associated with somnolence has been attributed to a localized lesion in the medullary portion of the central nervous system, even though there was little evidence of neurologic illness by history or physical examination.7, 8
It appeared likely that a better understanding of this problem could be obtained by a study
SIEKER HO, HEYMAN A, BIRCHFIELD RI. THE EFFECTS OF NATURAL SLEEP AND HYPERSOMNOLENT STATES ON RESPIRATORY FUNCTION12. Ann Intern Med. 1960;52:500–516. doi: 10.7326/0003-4819-52-3-500
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Published: Ann Intern Med. 1960;52(3):500-516.
Pulmonary/Critical Care, Sleep Disorders.
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