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This is an extremely well conceived exposition of current knowledge of body fluids as regards their volume, tonicity, composition, and acid-base balance. The author's thesis is deceptively simple: "Pathologic alterations in these functions represent dislocations from a normal equilibrium. . . ." This is in contrast to the easily accepted alternative which frequently leads us to believe that certain diseases produce specific, unique, pathophysiologic body water profiles.
With this thesis, normal physiology is considered in the first half of the book; the second half discusses clinical considerations. These are treated first as general problems; then in relation to specific clinical
Clinical Disorders of Hydration and Acid-Base Equilibrium.. Ann Intern Med. 1960;52:735. doi: 10.7326/0003-4819-52-3-735_1
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Published: Ann Intern Med. 1960;52(3):735.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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