RICHMOND W. SMITH JR., M.D.; WILLIAM R. EYLER, M.D.; RAYMOND C. MELLINGER, M.D.
Physicians generally agree that senile osteoporosis is encountered with increasing frequency, presumably due to the lengthening life span achieved during the last several decades. Back pain due to vertebral fracture is a common expression of this disorder, yet surprisingly little information is available regarding the incidence of vertebral atrophy in older persons. An opportunity to evaluate incidence was realized in our recent studies of adrenocortical function in patients with osteoporosis. Urinary 17-ketosteroid and 17-hydroxysteroid levels had been determined for a large number of women with symptomatic vertebral osteoporosis, but the data could not be interpreted for possible etiologic significance without
SMITH RW, EYLER WR, MELLINGER RC. ON THE INCIDENCE OF SENILE OSTEOPOROSIS1. Ann Intern Med. ;52:773–781. doi: 10.7326/0003-4819-52-4-773
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Published: Ann Intern Med. 1960;52(4):773-781.
Endocrine and Metabolism, Metabolic Bone Disorders.
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