LEO D. FREYDBERG, M.D.
Opinion differs greatly on the value of corticotropin in treating myasthenia gravis. A review in 19551 shows reports in the literature of only 50 cases so treated, with 25 markedly improved. Despite this seemingly good average, there are few new reports. The large medical centers to which greater numbers of these patients gravitate have tried corticotropin on only a few.
The use of corticotropin in myasthenia gravis was first considered when various investigators reported in 1943 that either corticotropin or adrenal cortex extracts would cause involution of the thymus and other lymphoid tissues.2, 3 On the basis of these findings,
FREYDBERG LD. THE PLACE OF CORTICOTROPIN IN THE TREATMENT OF MYASTHENIA GRAVIS(THE PLACE OF CORTICOTROPIN IN THE TREATMENT OF MYASTHENIA GRAVIS*). Ann Intern Med. 1960;52:806–818. doi: 10.7326/0003-4819-52-4-806
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Published: Ann Intern Med. 1960;52(4):806-818.
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