KURT DE CRINIS, M.D.; WALTER REDISCH, M.D., F.A.C.P.; VINCENT FONTANA, M.D.; ARTHUR LEWIS, M.D.; MARION B. SULZBERGER, M.D., F.A.C.P.; J. MURRAY STEELE, M.D.
There has been considerable interest for many years in vasomotor responses to nicotine and to the smoking (or chewing) of tobacco. There is almost complete agreement that smoking usually produces transient adrenergic stimulation via the sympathetic nervous system, followed by depression of sympathetic and parasympathetic ganglia.1-5 Vasoconstrictor response to tobacco smoking could not be found in sympathectomized limbs6 by the technic of toe plethysmography, which records practically skin flow only.
It has been fairly well established over the years that, in a certain percentage of subjects, smoking of tobacco causes vasoconstriction of peripheral vessels, as indicated by decrease in
DE CRINIS K, REDISCH W, FONTANA V, LEWIS A, SULZBERGER MB, STEELE JM. VASCULAR RESPONSES TO SMOKING TOBACCO COMPARED WITH RESPONSES TO SKIN TESTING OF TOBACCO EXTRACTS123. Ann Intern Med. ;52:1035–1041. doi: 10.7326/0003-4819-52-5-1035
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Published: Ann Intern Med. 1960;52(5):1035-1041.
Cardiology, Coronary Risk Factors, Smoking.
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