ANANDA S. PRASAD, M.B., B.S., Ph.D. (Med.)
Hemorrhagic tendency in polycythemia vera has been reported in the literature. However, bleeding severe enough to cause anemia and to mask the diagnosis of polycythemia vera is rare. A patient came to this hospital three years ago with anemia and splenomegaly thought to be due to agnogenic myeloid metaplasia. A diagnosis of polycythemia vera was made finally, and the bleeding tendency was attributed to a deficiency of the stable factor (synonyms: Factor VII, Proconvertin, SPCA). Later priapism developed, a rather rare thrombotic complication of this disease. Since the case is of unusual interest, it is believed to be worthy of
PRASAD AS. ANEMIA DUE TO STABLE FACTOR DEFICIENCY IN A PATIENT WITH POLYCYTHEMIA VERA1. Ann Intern Med. ;52:1108–1113. doi: 10.7326/0003-4819-52-5-1108
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Published: Ann Intern Med. 1960;52(5):1108-1113.
Coagulopathies, Hematology/Oncology, Red Cell Disorders.
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