ABRAHAM A. POLACHEK, M.D.; ROBERT F. WILLIARD, B.S.
It has been shown1, 2 that patients with steatorrhea, whether due to pancreatic insufficiency or malabsorption syndrome, have low blood I131 levels after a fat meal with radioiodinated triolein. The two conditions may be differentiated by giving an additional meal of the labeled hydrolysis product of fat, radioiodinated oleic acid.3-6 Normal blood levels of I131 are obtained in the group with pancreatic disease, contrasted with low levels in patients with intestinal malabsorption.
Substitution therapy with pancreatic extract for exocrine pancreatic insufficiency has been used for a long time. A preparation of desiccated hog pancreas with high lipolytic activity7 has been
POLACHEK AA, WILLIARD RF. I131-LABELED FAT AND PANCREATIN AS A DIFFERENTIAL ABSORPTION TEST IN PATIENTS WITH STEATORRHEA(I131-LABELED FAT AND PANCREATIN AS A DIFFERENTIAL ABSORPTION TEST IN PATIENTS WITH STEATORRHEA*). Ann Intern Med. 1960;52:1195–1200. doi: 10.7326/0003-4819-52-6-1195
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Published: Ann Intern Med. 1960;52(6):1195-1200.
Celiac Disease and Malabsorption, Gastroenterology/Hepatology.
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