PERRY R. AYRES, M.D., F.A.C.P.; THOMAS B. WILLIARD, M.D.
In 1955 Karmen, Wróblewski, and LaDue1 reported an accurate and simplified technic for the study of enzymes concerned with transamination of amino acids in human tissues. Of several enzymes studied, glutamic oxalacetic transaminase (GO-T) has been given the most attention, and estimation of its level in serum (SGO-T) has been widely accepted as an aid in the diagnosis of acute myocardial infarction. Determination of SGO-T levels has become one of the standard procedures available in the laboratories of most general hospitals.
SGO-T determination in patients suspected of myocardial infarction is especially valuable when clinical and electrocardiographic data are inconclusive. Because
AYRES PR, WILLIARD TB. SERUM GLUTAMIC OXALACETIC TRANSAMINASE LEVELS IN 266 SURGICAL PATIENTS1. Ann Intern Med. ;52:1279–1288. doi: 10.7326/0003-4819-52-6-1279
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Published: Ann Intern Med. 1960;52(6):1279-1288.
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