THOMAS H. SNIDER, M.D.; FREEMAN M. WILNER, M.D.; BENJAMIN M. LEWIS, M.D.
Recently a new, chronic pulmonary disease, characterized by nonspecific respiratory symptoms and specific x-ray and pathologic findings, has been described by Rosen, Castleman and Liebow.1 They named the disease pulmonary alveolar proteinosis, because of the homogeneous, PAS (para-aminosalicylic acid)-positive, proteinaceous material which was found filling the alveoli of lung specimens taken at biopsy and autopsy. After extensive study of these patients, their environment and contacts, no specific etiology for this disease could be found. They postulated that it might be related to some inhalant of an unknown nature. Because their first case was observed less than five years ago, there
SNIDER TH, WILNER FM, LEWIS BM. CARDIOPULMONARY PHYSIOLOGY IN A CASE OF PULMONARY ALVEOLAR PROTEINOSIS1. Ann Intern Med. ;52:1318–1328. doi: 10.7326/0003-4819-52-6-1318
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Published: Ann Intern Med. 1960;52(6):1318-1328.
Cardiac Diagnosis and Imaging, Cardiology, Hematology/Oncology.
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