LESLIE ZIEVE, M.D., F.A.C.P.; DAVID F. MENDELSON, M.D.; MARY GOEPFERT, M.D.
The neuropsychiatric complications of spontaneous or surgically induced portal-systemic shunts have been widely observed and extensively discussed, so the most frequent clinical patterns are now common knowledge. Various more obscure and infrequent but no less fascinating manifestations of these complications are becoming evident as our awareness of the clinical entity increases. Two such manifestations have been observed in patients described in this report. The first is the occurrence of extreme and progressive protein intolerance, with correction of the recurrent toxic states by large doses of arginine. The second, elaborated upon in the companion paper that follows, is the occurrence of
LESLIE ZIEVE, DAVID F. MENDELSON, MARY GOEPFERT. SHUNT ENCEPHALOMYELOPATHY. I. RECURRENT PROTEIN ENCEPHALOPATHY WITH RESPONSE TO ARGININE(SHUNT ENCEPHALOMYELOPATHY. I. RECURRENT PROTEIN ENCEPHALOPATHY WITH RESPONSE TO ARGININE*). Ann Intern Med. 1960;53:33–52. doi: 10.7326/0003-4819-53-1-33
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Published: Ann Intern Med. 1960;53(1):33-52.
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