ALBERTO HURTADO, M.D.
Continuous exposure to a high-altitude environment, where the lowered partial pressure of the oxygen in the inspired air originates a certain degree of hypoxia, demands some adaptative mechanisms. These, in general, and in their main objectives, introduce an economy in the drop of the pO2 gradient from alveolar air to tissue level, and make possible the acquisition and utilization of the oxygen in the cell metabolism. In our experience, and from observations carried out mainly in Morococha, Peru, at an altitude of 4,540 meters (14,900 feet), with an average barometric pressure of 444 mm. Hg, these mechanisms attain their highest
HURTADO A. SOME CLINICAL ASPECTS OF LIFE AT HIGH ALTITUDES1. Ann Intern Med. 1960;53:247–258. doi: 10.7326/0003-4819-53-2-247
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Published: Ann Intern Med. 1960;53(2):247-258.
Lupus Erythematosus, Pulmonary/Critical Care, Rheumatology.
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