GERALD P. RODNAN, M.D.; EDUARDO J. YUNIS, M.D.; ROBERT S. TOTTEN, M.D.
In commenting some years ago upon pathologic examination of the human joint, Hench compared this structure to an inviolate "sacred cow," and noted the infrequency of the study of joint tissue at otherwise extensive postmortem examination.1 Despite a recent plea for regular inspection at necropsy of the readily accessible sternoclavicular articulations,2 examination of the joints is frequently overlooked, and there has been a paucity of information concerning the appearance of the synovium in almost all except the more common forms of rheumatic disease. This deficiency was only partially offset by the use of open joint biopsy. While this means of
RODNAN GP, YUNIS EJ, TOTTEN RS. EXPERIENCE WITH PUNCH BIOPSY OF SYNOVIUM IN THE STUDY OF JOINT DISEASE12. Ann Intern Med. ;53:319–331. doi: 10.7326/0003-4819-53-2-319
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Published: Ann Intern Med. 1960;53(2):319-331.
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