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Heightened interest in fat metabolism followed demonstrations in the early 1940's that body fats were in a state of dynamic fatty acid exchange rather than simply inert storage substances as they had been thought to be. The availability of long-lived radioactive carbon isotope, C14, permitted rapid advances toward eventual delineation of the pathways of fat metabolism. During the 10 years that radioactive isotopes were applied to this problem, many aspects of fat and fatty acid metabolism were clarified; others, only approached. Frazer's radical "partition" theory of fat absorption was shown to be valid to the extent that short chain fatty
Radioisotope Studies of Fatty Acid Metabolism.. Ann Intern Med. ;53:621. doi: 10.7326/0003-4819-53-3-621_1
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Published: Ann Intern Med. 1960;53(3):621.
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