MARK E. WINFIELD, M.D.
Hemiballism is a hyperkinesia,1 consisting of bizarre involuntary movements, which occurs when the subthalamic nucleus of Luys or its pathways are damaged or destroyed.2-6 It has been shown in animal experiments that this lima bean-sized nucleus must be at least 20% destroyed for symptoms to be manifested clinically, and that a correlation exists between the severity of symptoms and the percentage of destruction.7 The nucleus appears to regulate cerebral coördination.5 Its destruction removes the regulating mechanism, and the resulting hemiballism is due to other surviving structures,8 since animal experiments prove that the involuntary movements are not produced by stimulation of
WINFIELD ME. TRANSIENT HEMIBALLISM1. Ann Intern Med. 1960;53:822–827. doi: 10.7326/0003-4819-53-4-822
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Published: Ann Intern Med. 1960;53(4):822-827.
Cardiology, Infectious Disease, Lupus Erythematosus, Rheumatology.
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