BORIS RUEBNER, M.D.
Myelosclerosis with a leuko-erythroblastic anemia and splenomegaly has become a well recognized clinical syndrome. Much controversy still surrounds its etiology, which may well be multiple.1 The present case is thought worth reporting because of the unusual situation and marked fibrosis of some of the extramedullary foci, and also because of the severity of the hepatic involvement.
History: A 67 year old night watchman of partly West Indian, partly European ancestry was first admitted to the Victoria General Hospital in 1951. He had been suffering from increasing weakness and fatigue during the preceding seven years.
On physical examination the
RUEBNER B. MYELOSCLEROSIS WITH SEROSAL MYELOID METAPLASIA AND FATAL LIVER INVOLVEMENT(MYELOSCLEROSIS WITH SEROSAL MYELOID METAPLASIA AND FATAL LIVER INVOLVEMENT*). Ann Intern Med. 1960;53:1075–1088. doi: 10.7326/0003-4819-53-5-1075
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Published: Ann Intern Med. 1960;53(5):1075-1088.
Gastroenterology/Hepatology, Liver Disease.
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