W. H. LYLE, M.D.; B. J. LEONARD, M.D.; W. E. BOWDEN, M.B., Ch.B.; D. G. MILLER, M.B., Ch.B.
The xanthomatoses are usually classified in two groups, one with normal, the other with raised levels of cholesterol in the blood. The first comprises Hand-Schüller-Christian disease, Letterer-Siwe disease, eosinophilic granuloma, and a number of formes frustes and mixtures of these. That these conditions, so diverse in their clinical presentation, are histologically similar is generally agreed.4 Rowland8 in 1928 showed that the foam cells which dermatologists had long known to be characteristic of the skin lesions of xanthoma disseminatum were also to be found in various tissues in Hand-Schüller-Christian disease, although the two conditions are rarely found in the same patient,
LYLE WH, LEONARD BJ, BOWDEN WE, MILLER DG. NORMOCHOLESTEROLEMIC XANTHOMATOSIS: REPORT OF A CASE WITH MYOCARDIAL FIBROSIS AND MYELOSCLEROSIS1. Ann Intern Med. ;53:1260–1270. doi: 10.7326/0003-4819-53-6-1260
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Published: Ann Intern Med. 1960;53(6):1260-1270.
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