ARLAN P. COHN, M.D.; AUGUST A. HOWARD, M.D.
The human leptospiral infections have been grouped into various clinical syndromes, such as a mild, grippelike illness, an aseptic meningitis, and a sometimes fatal complex of jaundice, nephritis, hemorrhage, and vascular collapse known as Weil's disease. A recent outbreak of leptospirosis on Okinawa among 11 U. S. Marines supports the observation of Asian, European, and American clinicians that leptospirosis most commonly presents as a mild illness, with only slight renal and hepatic damage, plus delayed signs of aseptic meningitis.
Edwards,1 in his recent study of 12 sporadic cases of leptospiral disease, has pointed out that this rather distinct, mild, and
COHN AP, HOWARD AA. COMMON CHARACTERISTICS OF LEPTOSPIROSIS: A REPORT ON 11 CASES1. Ann Intern Med. ;54:57–65. doi: 10.7326/0003-4819-54-1-57
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Published: Ann Intern Med. 1961;54(1):57-65.
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