SELIG M. GINSBURG, M.D.
Since Owren's description in 1948 of aplastic crisis in congenital hemolytic jaundice (1), crises have been demonstrated to occur in hemolytic disorders, including other cases of congenital hemolytic jaundice (2-6), sickle cell anemia (7-9), and acquired hemolytic anemia (3, 9, 10). However, it is not generally recognized that aplastic crisis may occur in an otherwise hematologically normal individual. Because of the implications of aplastic crisis in such an individual, and the infrequency with which this condition is reported, the following case may prove to be both interesting and informative.
A ten-year-old Puerto Rican girl was admitted to The
GINSBURG SM. Acute Erythroid Aplasia (Erythroblastopenia) and Vascular Purpura in an Otherwise Hematologically Normal Child. Ann Intern Med. 1961;55:317–321. doi: 10.7326/0003-4819-55-2-317
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Published: Ann Intern Med. 1961;55(2):317-321.
Hematology/Oncology, Red Cell Disorders.
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