WILLIAM J. PIEPER, M.D.; ROBERT J. RYAN, M.D.
This case is presented as an instance of spontaneous destruction of the pituitary in a patient with acromegaly. Trophic hormone deficiencies were permanent and necessitated replacement therapy.
The patient, a 43-year-old single white female, was admitted to the University of Illinois Research and Educational Hospitals Clinics in 1949 with the complaint of bilateral breast pain and nodularity. This was diagnosed as chronic cystic mastitis. Over the succeeding two years she was given several short trials of stilbestrol therapy.
She was next seen in 1954 with the complaints of intermittent edema of the eyelids and lips, acneform rash on
PIEPER WJ, RYAN RJ. Pituitary Apoplexy in a Patient with Acromegaly. Ann Intern Med. ;55:478–481. doi: 10.7326/0003-4819-55-3-478
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Published: Ann Intern Med. 1961;55(3):478-481.
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