WILLIAM S. CURRAN, M.D.; GEORGE GOLDMAN, M.D.
The incidence of immediate wheal and flare skin reactions1 among allergic and nonallergic individuals continues to evoke considerable discussion and is, as yet, far from settled. Clinical experience has shown that positive skin reactions are found very frequently among patients with allergic rhinitis, bronchial asthma, and infantile eczema. A recent study stated, in addition, "it is established that many normal2 people show a proportion of positive skin reactions to allergenic extracts" (1). As evidence for this assertion the work of Rackemann and Simon (2), Grow and Herman (3), and Herxheimer, Mclnvoy, Sutton, Utidjian, and Utidjian (4) was cited, all of
CURRAN WS, GOLDMAN G. The Incidence of Immediately Reacting Allergy Skin Tests in a "Normal" Adult Population. Ann Intern Med. ;55:777–783. doi: 10.7326/0003-4819-55-5-777
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Published: Ann Intern Med. 1961;55(5):777-783.
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