ELLIOTT F. OSSERMAN, M.D.
The three articles dealing with "amyloidosis" which appear in this issue of the ANNALS are testimony to the continuing interest in this vexingly obscure clinical and experimental phenomenon. Despite the extensive studies of the subject which have been carried out over the past several decades, the precise pathogenesis and exact biochemical nature of these infiltrates are still incompletely understood. Some progress has been made, however, and it may be in order to summarize briefly our present knowledge and some of the current "working hypotheses."
At the outset, it may be appropriate to examine and possibly to challenge the validity of
OSSERMAN EF. Amyloidosis: Tissue Proteinosis: Gammaloidosis. Ann Intern Med. ;55:1033–1036. doi: 10.7326/0003-4819-55-6-1033
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Published: Ann Intern Med. 1961;55(6):1033-1036.
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