EDWARD H. KASS, M.D., PH.D., F.A.C.P.
The changing pattern of infectious disease is well illustrated in the problem of pyelonephritis. In the past, clinically important infections were due largely to microorganisms that were "caught," that is, were not indigenous to the host. Socioeconomic patterns played important roles in determining the prevalence and pathogenesis of such infections. Now, increasing numbers of infections are due to Gram-negative rods, staphylococci, enterococci, and similar microorganisms that are not "caught" in the usual sense of the word, but are constantly present within the host. The presence of such organisms, and their capacity to cause clinical disease, seem to be influenced less
KASS EH. Pyelonephritis and Bacteriuria: A Major Problem in Preventive Medicine. Ann Intern Med. ;56:46–53. doi: 10.7326/0003-4819-56-1-46
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Published: Ann Intern Med. 1962;56(1):46-53.
Infectious Disease, Nephrology, Prevention/Screening, Urinary Tract Infection.
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