DONALD M. GINSBERG, M.D.
Recent reports (1, 2) indicate that osteogenesis imperfecta may be associated with elevated acid phosphatase levels. Our experience with 11 patients having this malady forms the basis of this report.
This study comprises [a] seven cases of active osteogenesis imperfecta in children with multiple recent fractures (Table 1, Cases 1-7), [b] three adults with burned-out osteogenesis imperfecta who suffered numerous fractures in childhood (Table 2, Cases 8-10), [c] the mother of a child with this disease who presented only with blue sclerae but who had never suffered a fracture (Table 3, Case 14), and [d] three other
GINSBERG DM. Normal Serum Acid Phosphatase Levels in Osteogenesis Imperfecta. Ann Intern Med. ;56:141–143. doi: 10.7326/0003-4819-56-1-141
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Published: Ann Intern Med. 1962;56(1):141-143.
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