ANGELO TARANTA, M.D.; MARIO SPAGNUOLO, M.D.; ALVAN R. FEINSTEIN, M.D.
Rheumatic fever has often been described in the past as a chronic disease (2) or as a disease of long duration (3). These descriptions were based on long-term follow-up studies of children who had had rheumatic fever, conducted in the period before widespread use of prophylaxis, and without the benefit of modern immunologic and bacteriologic techniques. The resulting image was of a disease that seemed, at first, to subside, only to reappear months or years later, often without any apparent cause. It was then concluded that the disease had subsided in appearance only; in reality, it had abated to a
TARANTA A, SPAGNUOLO M, FEINSTEIN AR. "Chronic" Rheumatic Fever. Ann Intern Med. ;56:367–388. doi: 10.7326/0003-4819-56-3-367
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Published: Ann Intern Med. 1962;56(3):367-388.
Infectious Disease, Rheumatology, Streptococcal Infections.
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