R. P. Howard, M.D., F.A.C.P.; R. H. Furman, M.D., F.A.C.P.
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The ability of estrogens to lower beta lipoprotein (C/P ratio 1.3) concentrations and increase alpha lipoprotein (C/P ratio 0.45) concentrations, resulting in a net increase in serum phospholipid levels, decrease in C/P, and relatively little change in cholesterol levels, is generally regarded as desirable, and provides a physico-chemical basis for the incidence of lower coronary disease in premenopausal women.
However, our studies in normal subjects indicate that premenopausal women differ from men and postmenopausal women alike, not in respect to alpha and beta lipoproteins, but in having significantly smaller amounts of cholesterol, phospholipid, and triglyceride in the form of low
Howard RP, Furman RH. Estrogens, Androgens, and Serum Lipids: The Enigmatic Triad of Atherogenesis.. Ann Intern Med. 1962;56:668. doi: 10.7326/0003-4819-56-4-668_2
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Published: Ann Intern Med. 1962;56(4):668.
Cardiology, Coronary Risk Factors, Dyslipidemia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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