R. G. Siekert, M.D., F.A.C.P.; J. P. Whisnant, M.D. (Assoc.); C. H. Millikan, M.D., F.A.C.P.
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In recent years the use of anticoagulant therapy and surgical therapy has been advocated for certain varieties of occlusive (ischemic) cerebrovascular disease. Some difference exists among the proponents of the various therapies as to the indications of each therapy in various clinical categories. Frequently, one therapy has been used to the exclusion of the other.
In general, six categories of patients must be considered in the evaluation of the usefulness of any therapy. There are the three clinical groups:  intermittent insufficiency (normal neurologic status);  progressing stroke (advancing neurologic deficit); and  completed stroke (stable neurologic deficit). Each of
Siekert RG, Whisnant JP, Millikan CH. Surgical and Anticoagulant Therapy of Occlusive Cerebrovascular Disease.. Ann Intern Med. ;56:671–672. doi: 10.7326/0003-4819-56-4-671_3
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Published: Ann Intern Med. 1962;56(4):671-672.
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